Tools to Maximize a National Investment in the GeneXpert July 22, 2013
There Are Four Stable, Scaling-up Data Services Around the GeneXpert GxAlert – – –
Open source, dev in 2012 by Abt Associates using their own money Incorporates diagnostics for TB and flu (GeneXpert) and HIV (PIMA) Active in India and Nigeria; early stage in 5 countries
TBGxMonitor – –
Developed in 2011 by Univ. of Witwatersand in South Africa Active in South Africa; early stage in 13 countries
XpertSMS – –
Open source, dev in 2011 by IRD Pakistan under one-time grant Active in Pakistan, Nepal, Kenya, Zimbabwe; early stage in 5 countries
The first three were developed out of necessity… teams just wanted the data. It turns out, others wanted the data too. So these developed into software products. There is some overlap, but generally each tool fits a different set of needs.
RemoteXpert – –
Being developed now by Cepheid, estimated launch December 2013 Pilot tested in South Africa
Abt Associates
What Does Each Software Do? Disease Management
Case+Population level Management Indicator reporting MDR treatment Drug demand / supply Integration into existing National Health Information Systems MOH messaging Clinic / lab messaging Patient messaging
Instrument Operations
Supply Chain Management
Errors and error rate (by user, module, and machine) External Quality Assurance (EQA) Instrument Verification Pre-analytical, analytical and post-analytical evaluation
Cartridge expirations Stockout management Utilization vs. disease load Deployment planning Procurement, warranty, and service planning
Abt Associates
A Look Inside…GxAlert
Abt Associates
Each is Relatively Inexpensive to Bring to National Scale
GxAlert ~$25,000 Yr1 to roll out nationwide and tech support existing software; Yr2 ~$10,000
XpertSMS ~$25,000 Yr1 to roll out nationwide and tech support existing software; Yr2 ~$10,000
TBGxMonitor available to complement NHLS/Wits DCS EQA program. Independent use cost TBD.
Cepheid’s RemoteXpert, cost TBD, Dec 2013 By leveraging these tools, you can: 1) 2) 3)
Shorten diagnostic response time from months to seconds, getting patients into treatment faster Reduce waste, operating costs, and stockouts Dramatically improve data quality
Organizations can pay for customizations if desired, but not necessary Each of these software is capable of communicating with the others so installing a mix of software is relatively Abt Associates easy and inexpensive
Why Include These Tools in Your GeneXpert Implementation? 1.
Shorten diagnostic response time from months to seconds, getting patients into treatment faster
2.
Reduce waste, operating costs, and stockouts
3.
Dramatically improve data quality
4.
Identify drug resistance patterns of TB strains
5.
Measure program adherence to the TB algorithms
6.
Order cartridges based on real-time demand forecasts
7.
…
Abt Associates
Better patient treatment Faster response to MDR-TB More efficient TB logistics
Prepared by: Martha Benezet
[email protected] Jeff Takle
[email protected] Download slide deck @ www.GxAlert.com
